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Early Seizures Prematurely Unsilence Auditory Synapses to Disrupt Thalamocortical Critical Period Plasticity
Heightened neural excitability in infancy and childhood results in increased susceptibility to seizures. Such early-life seizures are associated with language deficits and autism that can result from aberrant development of the auditory cortex. Here, we show that early-life seizures disrupt a critic...
Autores principales: | Sun, Hongyu, Takesian, Anne E., Wang, Ting Ting, Lippman-Bell, Jocelyn J., Hensch, Takao K., Jensen, Frances E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446922/ https://www.ncbi.nlm.nih.gov/pubmed/29847785 http://dx.doi.org/10.1016/j.celrep.2018.04.108 |
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