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Birthweight, Type 2 Diabetes Mellitus, and Cardiovascular Disease: Addressing the Barker Hypothesis With Mendelian Randomization
BACKGROUND: Low birthweight has been associated with a higher risk of hypertension, type 2 diabetes mellitus (T2D), and cardiovascular disease. The Barker hypothesis posits that intrauterine growth restriction resulting in lower birthweight is causal for these diseases, but causality is difficult to...
Autores principales: | Zanetti, Daniela, Tikkanen, Emmi, Gustafsson, Stefan, Priest, James R., Burgess, Stephen, Ingelsson, Erik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447084/ https://www.ncbi.nlm.nih.gov/pubmed/29875125 http://dx.doi.org/10.1161/CIRCGEN.117.002054 |
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