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Using selective lung injury to improve murine models of spatially heterogeneous lung diseases

Many lung diseases, such as the acute respiratory distress syndrome (ARDS), display significant regional heterogeneity with patches of severely injured tissue adjacent to apparently healthy tissue. Current mouse models that aim to mimic ARDS generally produce diffuse injuries that cannot reproducibl...

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Detalles Bibliográficos
Autores principales: Paris, Andrew J., Guo, Lei, Dai, Ning, Katzen, Jeremy B., Patel, Priyal N., Worthen, G. Scott, Brenner, Jacob S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447173/
https://www.ncbi.nlm.nih.gov/pubmed/30943189
http://dx.doi.org/10.1371/journal.pone.0202456

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