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A type III-A CRISPR-Cas system employs degradosome nucleases to ensure robust immunity

CRISPR-Cas systems provide sequence-specific immunity against phages and mobile genetic elements using CRISPR-associated nucleases guided by short CRISPR RNAs (crRNAs). Type III systems exhibit a robust immune response that can lead to the extinction of a phage population, a feat coordinated by a mu...

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Detalles Bibliográficos
Autores principales:	Chou-Zheng, Lucy, Hatoum-Aslan, Asma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447361/ https://www.ncbi.nlm.nih.gov/pubmed/30942690 http://dx.doi.org/10.7554/eLife.45393

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