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Intracranial Mature Teratoma in an Adult Patient: A Case Report
Introduction : Primary intracranial teratoma is a subtype of germ cell tumors, classified into three subtypes. They occur very rarely, with only several reported individual cases in adults. Case Description We present a patient with an intermittent headache in the right frontal region. Magnetic res...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447400/ https://www.ncbi.nlm.nih.gov/pubmed/31041158 http://dx.doi.org/10.1055/s-0039-1685213 |
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author | Romić, Dominik Raguž, Marina Marčinković, Petar Sesar, Patricija Špero, Martina Čolak Romić, Zrinka Dlaka, Domagoj Chudy, Darko |
author_facet | Romić, Dominik Raguž, Marina Marčinković, Petar Sesar, Patricija Špero, Martina Čolak Romić, Zrinka Dlaka, Domagoj Chudy, Darko |
author_sort | Romić, Dominik |
collection | PubMed |
description | Introduction : Primary intracranial teratoma is a subtype of germ cell tumors, classified into three subtypes. They occur very rarely, with only several reported individual cases in adults. Case Description We present a patient with an intermittent headache in the right frontal region. Magnetic resonance imaging (MRI) revealed a right sided high frontal parasagittal mass that compressed the falx, the right lateral ventricle, as well as the brain parenchyma. Patient underwent surgical treatment. Histopathological analysis described mature teratoma. Four months after the surgical treatment there were no signs of residual intracranial mass or relapse. Discussion Primary intracranial teratoma in adults has a nonspecific clinical presentation. MRI reveals a solitary irregular mass with multilocularity and mixed signals derived from different tissues. The patients age, biochemical markers, and patohistological analysis are necessary to confirm the diagnosis. Conclusion Teratoma treatment strategy still remains controversial. It includes radical resection whenever possible. Since the residual portion of mature teratoma may contain part of immature or malignant tissue, tumor recurrence after surgical removal is possible. Also, new tumor mass could occur at other sites intracranial after the initial one was removed. Thus, although patients usually recover, they should be followed-up for a long period of time. |
format | Online Article Text |
id | pubmed-6447400 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-64474002019-04-30 Intracranial Mature Teratoma in an Adult Patient: A Case Report Romić, Dominik Raguž, Marina Marčinković, Petar Sesar, Patricija Špero, Martina Čolak Romić, Zrinka Dlaka, Domagoj Chudy, Darko J Neurol Surg Rep Introduction : Primary intracranial teratoma is a subtype of germ cell tumors, classified into three subtypes. They occur very rarely, with only several reported individual cases in adults. Case Description We present a patient with an intermittent headache in the right frontal region. Magnetic resonance imaging (MRI) revealed a right sided high frontal parasagittal mass that compressed the falx, the right lateral ventricle, as well as the brain parenchyma. Patient underwent surgical treatment. Histopathological analysis described mature teratoma. Four months after the surgical treatment there were no signs of residual intracranial mass or relapse. Discussion Primary intracranial teratoma in adults has a nonspecific clinical presentation. MRI reveals a solitary irregular mass with multilocularity and mixed signals derived from different tissues. The patients age, biochemical markers, and patohistological analysis are necessary to confirm the diagnosis. Conclusion Teratoma treatment strategy still remains controversial. It includes radical resection whenever possible. Since the residual portion of mature teratoma may contain part of immature or malignant tissue, tumor recurrence after surgical removal is possible. Also, new tumor mass could occur at other sites intracranial after the initial one was removed. Thus, although patients usually recover, they should be followed-up for a long period of time. Georg Thieme Verlag KG 2019-01 2019-04-03 /pmc/articles/PMC6447400/ /pubmed/31041158 http://dx.doi.org/10.1055/s-0039-1685213 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Romić, Dominik Raguž, Marina Marčinković, Petar Sesar, Patricija Špero, Martina Čolak Romić, Zrinka Dlaka, Domagoj Chudy, Darko Intracranial Mature Teratoma in an Adult Patient: A Case Report |
title | Intracranial Mature Teratoma in an Adult Patient: A Case Report |
title_full | Intracranial Mature Teratoma in an Adult Patient: A Case Report |
title_fullStr | Intracranial Mature Teratoma in an Adult Patient: A Case Report |
title_full_unstemmed | Intracranial Mature Teratoma in an Adult Patient: A Case Report |
title_short | Intracranial Mature Teratoma in an Adult Patient: A Case Report |
title_sort | intracranial mature teratoma in an adult patient: a case report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447400/ https://www.ncbi.nlm.nih.gov/pubmed/31041158 http://dx.doi.org/10.1055/s-0039-1685213 |
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