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TagGraph reveals vast protein modification landscapes from large tandem mass spectrometry data sets
Although mass spectrometry is well-suited to identifying thousands of possible protein post-translational modifications (PTMs), it has historically been biased towards just a few. To measure the entire set of PTMs across diverse proteomes, software must overcome the dual challenges of searching enor...
Autores principales: | Devabhaktuni, Arun, Lin, Sarah, Zhang, Lichao, Swaminathan, Kavya, Gonzales, Carlos, Olsson, Niclas, Pearlman, Sam, Rawson, Keith, Elias, Joshua E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447449/ https://www.ncbi.nlm.nih.gov/pubmed/30936560 http://dx.doi.org/10.1038/s41587-019-0067-5 |
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