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TagGraph reveals vast protein modification landscapes from large tandem mass spectrometry data sets

Although mass spectrometry is well-suited to identifying thousands of possible protein post-translational modifications (PTMs), it has historically been biased towards just a few. To measure the entire set of PTMs across diverse proteomes, software must overcome the dual challenges of searching enor...

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Detalles Bibliográficos
Autores principales: Devabhaktuni, Arun, Lin, Sarah, Zhang, Lichao, Swaminathan, Kavya, Gonzales, Carlos, Olsson, Niclas, Pearlman, Sam, Rawson, Keith, Elias, Joshua E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447449/
https://www.ncbi.nlm.nih.gov/pubmed/30936560
http://dx.doi.org/10.1038/s41587-019-0067-5

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