Cargando…

HIV-1 envelope glycoproteins isolated from Viremic Non-Progressor individuals are fully functional and cytopathic

In untreated HIV-1-infected individuals, viremia is positively associated with disease progression. However, some viremic non progressors (VNPs) individuals show paradoxical high CD4(+) T cell counts. HIV-1 envelope glycoprotein complex (Env) is a major cytopathic determinant in viral replication; t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cabrera-Rodríguez, Romina, Hebmann, Veronique, Marfil, Silvia, Pernas, María, Marrero-Hernández, Sara, Cabrera, Cecilia, Urrea, Victor, Casado, Concepción, Olivares, Isabel, Márquez-Arce, Daniel, Pérez-Yanes, Silvia, Estévez-Herrera, Judith, Clotet, Bonaventura, Espert, Lucile, López-Galíndez, Cecilio, Biard-Piechaczyk, Martine, Valenzuela-Fernández, Agustín, Blanco, Julià
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447548/ https://www.ncbi.nlm.nih.gov/pubmed/30944395 http://dx.doi.org/10.1038/s41598-019-42075-3

Ejemplares similares

The Characteristics of the HIV-1 Env Glycoprotein Are Linked With Viral Pathogenesis
por: Pérez-Yanes, Silvia, et al.
Publicado: (2022)

Viremic HIV Infected Individuals with High CD4 T Cells and Functional Envelope Proteins Show Anti-gp41 Antibodies with Unique Specificity and Function
por: Curriu, Marta, et al.
Publicado: (2012)

Contribution of the HIV-1 Envelope Glycoprotein to AIDS Pathogenesis and Clinical Progression
por: Valenzuela-Fernández, Agustín, et al.
Publicado: (2022)

Viral and Cellular Factors Leading to the Loss of CD4 Homeostasis in HIV-1 Viremic Nonprogressors
por: Colomer-Lluch, Marta, et al.
Publicado: (2022)

Differential Role of Autophagy in CD4 T Cells and Macrophages during X4 and R5 HIV-1 Infection
por: Espert, Lucile, et al.
Publicado: (2009)

Macroautophagy Regulation during HIV-1 Infection of CD4+ T Cells and Macrophages
por: Borel, Sophie, et al.
Publicado: (2012)

Involvement of autophagy in viral infections: antiviral function and subversion by viruses
por: Espert, Lucile, et al.
Publicado: (2007)

The Interplay of HIV and Autophagy in Early Infection
por: Cabrera-Rodríguez, Romina, et al.
Publicado: (2021)

Autophagy plays an essential role in HIV-1 infection
por: Robert-Hebmann, V, et al.
Publicado: (2009)

The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype
por: Cunyat, Francesc, et al.
Publicado: (2012)

Low levels of anti-MPER antibodies are detectable in viremic HIV infected
por: Carrillo, J, et al.
Publicado: (2012)

Apoptosis of uninfected cells induced by HIV envelope glycoproteins
por: Ahr, Barbara, et al.
Publicado: (2004)

Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals
por: Weber, Jan, et al.
Publicado: (2017)

Viral Characteristics Associated with the Clinical Nonprogressor Phenotype Are Inherited by Viruses from a Cluster of HIV-1 Elite Controllers
por: Casado, Concepción, et al.
Publicado: (2018)

Regulation of Innate Immune Responses by Autophagy: A Goldmine for Viruses
por: Pradel, Baptiste, et al.
Publicado: (2020)

Differential MicroRNA Expression Profile between Stimulated PBMCs from HIV-1 Infected Elite Controllers and Viremic Progressors
por: Egaña-Gorroño, Lander, et al.
Publicado: (2014)

Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors
por: Gaardbo, Julie Christine, et al.
Publicado: (2013)

Control of HIV-1 Pathogenesis in Viremic Nonprogressors Is Independent of Gag-Specific Cytotoxic T Lymphocyte Responses
por: Salgado, Maria, et al.
Publicado: (2018)

LYSOSOMAL ENZYMES IN CELLS INFECTED WITH CYTOPATHIC AND NON-CYTOPATHIC VIRUSES
por: Mallucci, L., et al.
Publicado: (1965)

HIV-1 Nef Targets HDAC6 to Assure Viral Production and Virus Infection
por: Marrero-Hernández, Sara, et al.
Publicado: (2019)

Octogenarians with chronic kidney disease in the nephrology clinic: Progressors vs. non-progressors
por: Frías, Aida, et al.
Publicado: (2023)

TDP-43 Controls HIV-1 Viral Production and Virus Infectiveness
por: Cabrera-Rodríguez, Romina, et al.
Publicado: (2023)

HIV Infection: Shaping the Complex, Dynamic, and Interconnected Network of the Cytoskeleton
por: Cabrera-Rodríguez, Romina, et al.
Publicado: (2023)

Immunoescape of HIV-1 in Env-EL9 CD8 + T cell response restricted by HLA-B*14:02 in a Non progressor who lost twenty-seven years of HIV-1 control
por: Moyano, Ana, et al.
Publicado: (2022)

Remodeling the bladder tumor immune microenvironment by mycobacterial species with changes in their cell envelope composition
por: Senserrich, Jordi, et al.
Publicado: (2022)

Transplantation of HCV Viremic Livers into HCV Viremic Recipients Followed by Direct-acting Antiviral Therapy
por: Kapila, Nikhil, et al.
Publicado: (2019)

Zika Virus Pathogenesis: A Battle for Immune Evasion
por: Estévez-Herrera, Judith, et al.
Publicado: (2021)

Cytopathic Mechanisms of HIV-1
por: Costin, Joshua M
Publicado: (2007)

Impact of chemotherapy and/or immunotherapy on neutralizing antibody response to SARS‐CoV‐2 mRNA‐1237 vaccine in patients with solid tumors
por: Felip, Eudald, et al.
Publicado: (2022)

Preserved immune functionality and high CMV-specific T-cell responses in HIV-infected individuals with poor CD4(+) T-cell immune recovery
por: Gómez-Mora, Elisabet, et al.
Publicado: (2017)

Analysis of Bovine Viral Diarrhea Viruses-infected monocytes: identification of cytopathic and non-cytopathic biotype differences
por: Ammari, Mais, et al.
Publicado: (2010)

Are Long-Term Non-Progressors Very Slow Progressors? Insights from the Chelsea and Westminster HIV Cohort, 1988–2010
por: Mandalia, Sundhiya, et al.
Publicado: (2012)

Viral Reservoirs in Lymph Nodes of FIV-Infected Progressor and Long-Term Non-Progressor Cats during the Asymptomatic Phase
por: Eckstrand, C. D., et al.
Publicado: (2016)

Bench-to-bedside review: Cytopathic hypoxia
por: Fink, Mitchell P
Publicado: (2002)

Transcriptomic Analysis of MDBK Cells Infected with Cytopathic and Non-Cytopathic Strains of Bovine Viral Diarrhea Virus (BVDV)
por: Mirosław, Paweł, et al.
Publicado: (2022)

Array Comparative Genomic Hybridization in Ulcerative Colitis Neoplasia: Single Non-Dysplastic Biopsies Distinguish Progressors from Non-Progressors
por: Bronner, Mary P., et al.
Publicado: (2010)

Factors associated with conversion of long-term non-progressors to progressors: A prospective study of HIV perinatally infected paediatric survivors
por: Radhakrishna, Muttineni, et al.
Publicado: (2013)

Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen
por: Rodon, Jordi, et al.
Publicado: (2021)

The Autophagy Nucleation Factor ATG9 Forms Nanoclusters with the HIV-1 Receptor DC-SIGN and Regulates Early Antiviral Autophagy in Human Dendritic Cells
por: Papin, Laure, et al.
Publicado: (2023)

Outcome of Kidney Transplants from Viremic and Non-Viremic Hepatitis C Virus Positive Donors into Negative Recipients: Results of the Spanish Registry
por: Franco, Antonio, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kpe174fpeo0ddmlno2pe25h74g