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Assessment of corneal substrate biomechanics and its effect on epithelial stem cell maintenance and differentiation
Whilst demonstrated extensively in vitro, the control of cell behaviour via modulation of substrate compliance in live tissues has not been accomplished to date. Here we propose that stem cells can be regulated solely through in situ modulation of tissue biomechanics. By first establishing, via high...
Autores principales: | Gouveia, Ricardo M., Lepert, Guillaume, Gupta, Suneel, Mohan, Rajiv R., Paterson, Carl, Connon, Che J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447573/ https://www.ncbi.nlm.nih.gov/pubmed/30944320 http://dx.doi.org/10.1038/s41467-019-09331-6 |
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