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Toxicological testing of allogeneic secretome derived from peripheral mononuclear cells (APOSEC): a novel cell-free therapeutic agent in skin disease
A cell-free approach using secretomes derived from stem cells or peripheral blood mononuclear cells is an active area of regenerative medicine that holds promise for therapies. Regulatory authorities classify these secretomes as biological medicinal products, and non- clinical safety assessment thus...
Autores principales: | Wuschko, Silvio, Gugerell, Alfred, Chabicovsky, Monika, Hofbauer, Helmut, Laggner, Maria, Erb, Michael, Ostler, Tobias, Peterbauer, Anja, Suessner, Susanne, Demyanets, Svitlana, Leuschner, Jost, Moser, Bernhard, Mildner, Michael, Ankersmit, Hendrik J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447581/ https://www.ncbi.nlm.nih.gov/pubmed/30944367 http://dx.doi.org/10.1038/s41598-019-42057-5 |
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