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GRSF1 is an age-related regulator of senescence

Senescent cells that accumulate in multiple tissues with age are thought to increase pathological phenotypes. The removal of senescent cells can improve lifespan and/or healthspan in mouse models. Global hypomethylation and local hypermethylation in DNA are hallmarks of aging but it is unclear if su...

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Detalles Bibliográficos
Autores principales: Kim, Su-Jeong, Chun, Maria, Wan, Junxiang, Lee, Changhan, Yen, Kelvin, Cohen, Pinchas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447602/
https://www.ncbi.nlm.nih.gov/pubmed/30944385
http://dx.doi.org/10.1038/s41598-019-42064-6