The C Allele of ATM rs11212617 Associates With Higher Pathological Complete Remission Rate in Breast Cancer Patients Treated With Neoadjuvant Metformin

Background: The minor allele (C) of the single-nucleotide polymorphism (SNP) rs11212617, located near the ataxia telangiectasia mutated (ATM) gene, has been associated with an increased likelihood of treatment success with metformin in type 2 diabetes. We herein investigated whether the same SNP wou...

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Detalles Bibliográficos
Autores principales: Cuyàs, Elisabet, Buxó, Maria, Ferri Iglesias, Maria José, Verdura, Sara, Pernas, Sonia, Dorca, Joan, Álvarez, Isabel, Martínez, Susana, Pérez-Garcia, Jose Manuel, Batista-López, Norberto, Rodríguez-Sánchez, César A., Amillano, Kepa, Domínguez, Severina, Luque, Maria, Morilla, Idoia, Stradella, Agostina, Viñas, Gemma, Cortés, Javier, Joven, Jorge, Brunet, Joan, López-Bonet, Eugeni, Garcia, Margarita, Saidani, Samiha, Queralt Moles, Xavier, Martin-Castillo, Begoña, Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447648/
https://www.ncbi.nlm.nih.gov/pubmed/30984619
http://dx.doi.org/10.3389/fonc.2019.00193

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