Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger?

Here we present a 79-year old man with chronic hypersensitivity pneumonitis probably caused by fungal contamination of a bagpipe. Several samples were taken from the patient's bagpipe. Four potential fungal antigens (Exophiala phaeomuriformis, Kwoniella europaea, Pyrenochaeta unguis-hominis and...

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Autores principales: Ziegler, Katharina, Joest, Marcus, Turan, Nesrin, Schmidt, Dirk, Rath, Peter-Michael, Steinmann, Joerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447729/
https://www.ncbi.nlm.nih.gov/pubmed/30989036
http://dx.doi.org/10.1016/j.mmcr.2019.03.005
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author Ziegler, Katharina
Joest, Marcus
Turan, Nesrin
Schmidt, Dirk
Rath, Peter-Michael
Steinmann, Joerg
author_facet Ziegler, Katharina
Joest, Marcus
Turan, Nesrin
Schmidt, Dirk
Rath, Peter-Michael
Steinmann, Joerg
author_sort Ziegler, Katharina
collection PubMed
description Here we present a 79-year old man with chronic hypersensitivity pneumonitis probably caused by fungal contamination of a bagpipe. Several samples were taken from the patient's bagpipe. Four potential fungal antigens (Exophiala phaeomuriformis, Kwoniella europaea, Pyrenochaeta unguis-hominis and Aureobasidium melanogenum) as potential trigger of hypersensitivity pneumonitis were identified. A serum ELISA test with Exophiala phaeomuriformis indicated reactivity. Cessation of playing the bagpipe and application of glucocorticoids lead to an improvement of the patient's symptoms.
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spelling pubmed-64477292019-04-15 Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger? Ziegler, Katharina Joest, Marcus Turan, Nesrin Schmidt, Dirk Rath, Peter-Michael Steinmann, Joerg Med Mycol Case Rep Case Report Here we present a 79-year old man with chronic hypersensitivity pneumonitis probably caused by fungal contamination of a bagpipe. Several samples were taken from the patient's bagpipe. Four potential fungal antigens (Exophiala phaeomuriformis, Kwoniella europaea, Pyrenochaeta unguis-hominis and Aureobasidium melanogenum) as potential trigger of hypersensitivity pneumonitis were identified. A serum ELISA test with Exophiala phaeomuriformis indicated reactivity. Cessation of playing the bagpipe and application of glucocorticoids lead to an improvement of the patient's symptoms. Elsevier 2019-03-26 /pmc/articles/PMC6447729/ /pubmed/30989036 http://dx.doi.org/10.1016/j.mmcr.2019.03.005 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ziegler, Katharina
Joest, Marcus
Turan, Nesrin
Schmidt, Dirk
Rath, Peter-Michael
Steinmann, Joerg
Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger?
title Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger?
title_full Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger?
title_fullStr Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger?
title_full_unstemmed Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger?
title_short Hypersensitivity pneumonitis of a bagpipe player: Fungal antigens as trigger?
title_sort hypersensitivity pneumonitis of a bagpipe player: fungal antigens as trigger?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447729/
https://www.ncbi.nlm.nih.gov/pubmed/30989036
http://dx.doi.org/10.1016/j.mmcr.2019.03.005
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