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Sulfasalazine could modulate the CD44v9‐xCT system and enhance cisplatin‐induced cytotoxic effects in metastatic bladder cancer

The prognostic role of CD44v9, a variant isoform of CD44 and a new cell surface marker of cancer stem cells, remains unclear in bladder cancer (BC) patients. Furthermore, limited information is available on the functional role of sulfasalazine (SSZ), which could modulate the CD44v9‐xCT system in ord...

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Detalles Bibliográficos
Autores principales: Ogihara, Koichiro, Kikuchi, Eiji, Okazaki, Shogo, Hagiwara, Masayuki, Takeda, Toshikazu, Matsumoto, Kazuhiro, Kosaka, Takeo, Mikami, Shuji, Saya, Hideyuki, Oya, Mototsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447829/
https://www.ncbi.nlm.nih.gov/pubmed/30719824
http://dx.doi.org/10.1111/cas.13960