GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice

The transcription factor GATA2 regulates normal hematopoiesis, particularly in‐ stem cell maintenance and myeloid differentiation. Various heteroallelic GATA2 gene mutations are associated with a variety of hematological neoplasms, including myelodysplastic syndromes and leukemias. Here, we report t...

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Detalles Bibliográficos
Autores principales: Harada, Nobuhiko, Hasegawa, Atsushi, Hirano, Ikuo, Yamamoto, Masayuki, Shimizu, Ritsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832/
https://www.ncbi.nlm.nih.gov/pubmed/30710465
http://dx.doi.org/10.1111/cas.13959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832/
https://www.ncbi.nlm.nih.gov/pubmed/30710465
http://dx.doi.org/10.1111/cas.13959

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