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UNC5D, suppressed by promoter hypermethylation, inhibits cell metastasis by activating death‐associated protein kinase 1 in prostate cancer

Prostate cancer (PCa) death primarily occurs due to metastasis of the cells, but little is known about the underlying molecular mechanisms. This study aimed to evaluate the expression of UNC5D, a newly identified tumor suppressor gene, analyze its epigenetic alterations, and elucidate its functional...

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Detalles Bibliográficos
Autores principales: Dong, Dong, Zhang, Lufang, Bai, Changsen, Ma, Na, Ji, Wei, Jia, Li, Zhang, Aimin, Zhang, Pengyu, Ren, Li, Zhou, Yunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447834/
https://www.ncbi.nlm.nih.gov/pubmed/30632669
http://dx.doi.org/10.1111/cas.13935