Combination of phospholipase Cε knockdown with GANT61 sensitizes castration-resistant prostate cancer cells to enzalutamide by suppressing the androgen receptor signaling pathway

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Castration-resistant prostate cancer (CRPC) is a major challenge in the treatment of prostate cancer (PCa). Phospholipase Cε (PLCε), an oncogene, has been found to be involved in the carcinogenesis, tumor proliferation and migration of several types of cancer. The effects, however, of PLCε on CRPC r...

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Detalles Bibliográficos
Autores principales: Sun, Wei, Li, Luo, Du, Zhongbo, Quan, Zhen, Yuan, Mengjuan, Cheng, Honglin, Gao, Yingying, Luo, Chunli, Wu, Xiaohou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448124/
https://www.ncbi.nlm.nih.gov/pubmed/30864728
http://dx.doi.org/10.3892/or.2019.7054
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