Cargando…
Global assessment of migraine severity measure: preliminary evidence of construct validity
BACKGROUND: In persons with migraine, severity of migraine is an important determinant of several health outcomes (e.g., patient quality of life and health care resource utilization). This study investigated how migraine patients rate the severity of their disease and how these ratings correlate wit...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448190/ https://www.ncbi.nlm.nih.gov/pubmed/30947702 http://dx.doi.org/10.1186/s12883-019-1284-8 |
_version_ | 1783408648573157376 |
---|---|
author | Sajobi, Tolulope T. Amoozegar, Farnaz Wang, Meng Wiebe, Natalie Fiest, Kirsten M. Patten, Scott B. Jette, Nathalie |
author_facet | Sajobi, Tolulope T. Amoozegar, Farnaz Wang, Meng Wiebe, Natalie Fiest, Kirsten M. Patten, Scott B. Jette, Nathalie |
author_sort | Sajobi, Tolulope T. |
collection | PubMed |
description | BACKGROUND: In persons with migraine, severity of migraine is an important determinant of several health outcomes (e.g., patient quality of life and health care resource utilization). This study investigated how migraine patients rate the severity of their disease and how these ratings correlate with their socio-demographic, clinical, and psycho-social characteristics. METHODS: This is a cohort of 263 adult migraine patients consecutively enrolled in the Neurological Disease and Depression Study (NEEDs). We obtained a broad range of clinical and patient-reported measures (e.g., patients’ ratings of migraine severity using the Global Assessment of Migraine Severity (GAMS), and migraine-related disability, as measured by the Migraine Disability Scale (MIDAS)). Depression was measured using the 9-item Patient Health Questionnaire (PHQ-9) and the 14-item Hospital Anxiety and Depression Scale (HADS). Median regression analysis was used to examine the predictors of patient ratings of migraine severity. RESULTS: The mean age for the patients was 42.5 years (SD = 13.2). While 209 (79.4%) patients were females, 177 (67.4%) participants reported “moderately severe” to “extremely severe” migraine on the GAMS, and 100 (31.6%) patients had chronic migraine. Patients’ report of severity on the GAMS was strongly correlated with patients’ ratings of MIDAS global severity question, overall MIDAS score, migraine type, PHQ-9 score, and frequency of migraine attacks. Mediation analyses revealed that MIDAS mediated the effect of depression on patient ratings of migraine severity, accounting for about 32% of the total effect of depression. Overall, migraine subtype, frequency of migraine, employment status, depression, and migraine-related disability were statistically significant predictors of patient-ratings of migraine severity. CONCLUSIONS: This study highlights the impact of clinical and psychosocial determinants of patient-ratings of migraine severity. GAMS is a brief and valid tool that can be used to assess migraine severity in busy clinical settings. |
format | Online Article Text |
id | pubmed-6448190 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-64481902019-04-15 Global assessment of migraine severity measure: preliminary evidence of construct validity Sajobi, Tolulope T. Amoozegar, Farnaz Wang, Meng Wiebe, Natalie Fiest, Kirsten M. Patten, Scott B. Jette, Nathalie BMC Neurol Research Article BACKGROUND: In persons with migraine, severity of migraine is an important determinant of several health outcomes (e.g., patient quality of life and health care resource utilization). This study investigated how migraine patients rate the severity of their disease and how these ratings correlate with their socio-demographic, clinical, and psycho-social characteristics. METHODS: This is a cohort of 263 adult migraine patients consecutively enrolled in the Neurological Disease and Depression Study (NEEDs). We obtained a broad range of clinical and patient-reported measures (e.g., patients’ ratings of migraine severity using the Global Assessment of Migraine Severity (GAMS), and migraine-related disability, as measured by the Migraine Disability Scale (MIDAS)). Depression was measured using the 9-item Patient Health Questionnaire (PHQ-9) and the 14-item Hospital Anxiety and Depression Scale (HADS). Median regression analysis was used to examine the predictors of patient ratings of migraine severity. RESULTS: The mean age for the patients was 42.5 years (SD = 13.2). While 209 (79.4%) patients were females, 177 (67.4%) participants reported “moderately severe” to “extremely severe” migraine on the GAMS, and 100 (31.6%) patients had chronic migraine. Patients’ report of severity on the GAMS was strongly correlated with patients’ ratings of MIDAS global severity question, overall MIDAS score, migraine type, PHQ-9 score, and frequency of migraine attacks. Mediation analyses revealed that MIDAS mediated the effect of depression on patient ratings of migraine severity, accounting for about 32% of the total effect of depression. Overall, migraine subtype, frequency of migraine, employment status, depression, and migraine-related disability were statistically significant predictors of patient-ratings of migraine severity. CONCLUSIONS: This study highlights the impact of clinical and psychosocial determinants of patient-ratings of migraine severity. GAMS is a brief and valid tool that can be used to assess migraine severity in busy clinical settings. BioMed Central 2019-04-04 /pmc/articles/PMC6448190/ /pubmed/30947702 http://dx.doi.org/10.1186/s12883-019-1284-8 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Sajobi, Tolulope T. Amoozegar, Farnaz Wang, Meng Wiebe, Natalie Fiest, Kirsten M. Patten, Scott B. Jette, Nathalie Global assessment of migraine severity measure: preliminary evidence of construct validity |
title | Global assessment of migraine severity measure: preliminary evidence of construct validity |
title_full | Global assessment of migraine severity measure: preliminary evidence of construct validity |
title_fullStr | Global assessment of migraine severity measure: preliminary evidence of construct validity |
title_full_unstemmed | Global assessment of migraine severity measure: preliminary evidence of construct validity |
title_short | Global assessment of migraine severity measure: preliminary evidence of construct validity |
title_sort | global assessment of migraine severity measure: preliminary evidence of construct validity |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448190/ https://www.ncbi.nlm.nih.gov/pubmed/30947702 http://dx.doi.org/10.1186/s12883-019-1284-8 |
work_keys_str_mv | AT sajobitolulopet globalassessmentofmigraineseveritymeasurepreliminaryevidenceofconstructvalidity AT amoozegarfarnaz globalassessmentofmigraineseveritymeasurepreliminaryevidenceofconstructvalidity AT wangmeng globalassessmentofmigraineseveritymeasurepreliminaryevidenceofconstructvalidity AT wiebenatalie globalassessmentofmigraineseveritymeasurepreliminaryevidenceofconstructvalidity AT fiestkirstenm globalassessmentofmigraineseveritymeasurepreliminaryevidenceofconstructvalidity AT pattenscottb globalassessmentofmigraineseveritymeasurepreliminaryevidenceofconstructvalidity AT jettenathalie globalassessmentofmigraineseveritymeasurepreliminaryevidenceofconstructvalidity |