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A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations

BACKGROUND: Multi-walled carbon nanotubes (MWCNT) have been shown to elicit the release of inflammatory and pro-fibrotic mediators, as well as histopathological changes in lungs of exposed animals. Current standards for testing MWCNTs and other nanoparticles (NPs) rely on low-throughput in vivo stud...

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Detalles Bibliográficos
Autores principales: Kabadi, Pranita K., Rodd, April L., Simmons, Alysha E., Messier, Norma J., Hurt, Robert H., Kane, Agnes B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448215/
https://www.ncbi.nlm.nih.gov/pubmed/30943996
http://dx.doi.org/10.1186/s12989-019-0298-0

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