Equilibrium of the intracellular redox state for improving cell growth and l-lysine yield of Corynebacterium glutamicum by optimal cofactor swapping

BACKGROUND: NAD(H/(+)) and NADP(H/(+)) are the most important redox cofactors in bacteria. However, the intracellular redox balance is in advantage of the cell growth and production of NAD(P)H-dependent products. RESULTS: In this paper, we rationally engineered glyceraldehyde-3-phosphate dehydrogena...

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Detalles Bibliográficos
Autores principales: Xu, Jian-Zhong, Ruan, Hao-Zhe, Chen, Xiu-Lai, Zhang, Feng, Zhang, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448238/
https://www.ncbi.nlm.nih.gov/pubmed/30943966
http://dx.doi.org/10.1186/s12934-019-1114-0

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