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(p)NNS-Conjugated Chitosan Mediated IGF-1 and miR-140 Overexpression in Articular Chondrocytes Improves Cartilage Repair

The aim of the present study was to investigate the effects of phosphorylatable nucleus localization signal linked nucleic kinase substrate short peptide ((p)NNS)-conjugated chitosan ((p)NNS-CS) mediated miR-140 and IGF-1 in both rabbit chondrocytes and cartilage defects model. (p)NNS-CS was combine...

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Detalles Bibliográficos
Autores principales:	Zhao, Rong-lan, Zhang, Xu-mei, Jia, Li-na, Song, Wei, Sun, Yan-li, Meng, Xiang-ying, Peng, Xiao-xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448336/ https://www.ncbi.nlm.nih.gov/pubmed/31016187 http://dx.doi.org/10.1155/2019/2761241

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