Cargando…

Assessing Amyloid Pathology in Cognitively Normal Subjects Using (18)F-Flutemetamol PET: Comparing Visual Reads and Quantitative Methods

Our objective was to determine the optimal approach for assessing amyloid disease in a cognitively normal elderly population. Methods: Dynamic (18)F-flutemetamol PET scans were acquired using a coffee-break protocol (a 0- to 30-min scan and a 90- to 110-min scan) on 190 cognitively normal elderly in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Collij, Lyduine E., Konijnenberg, Elles, Reimand, Juhan, Kate, Mara ten, den Braber, Anouk, Alves, Isadora Lopes, Zwan, Marissa, Yaqub, Maqsood, van Assema, Daniëlle M.E., Wink, Alle Meije, Lammertsma, Adriaan A., Scheltens, Philip, Visser, Pieter Jelle, Barkhof, Frederik, van Berckel, Bart N.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society of Nuclear Medicine 2019
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448465/ https://www.ncbi.nlm.nih.gov/pubmed/30315145 http://dx.doi.org/10.2967/jnumed.118.211532

Ejemplares similares

Visual assessment of [(18)F]flutemetamol PET images can detect early amyloid pathology and grade its extent
por: Collij, Lyduine E., et al.
Publicado: (2021)

White matter microstructure disruption in early stage amyloid pathology
por: Collij, Lyduine E., et al.
Publicado: (2021)

Amyloid-driven disruption of default mode network connectivity in cognitively healthy individuals
por: Ingala, Silvia, et al.
Publicado: (2021)

Regional amyloid accumulation predicts memory decline in initially cognitively unimpaired individuals
por: Collij, Lyduine E., et al.
Publicado: (2021)

Diagnostic impact of [(18)F]flutemetamol PET in early-onset dementia
por: Zwan, Marissa D., et al.
Publicado: (2017)

Multitracer model for staging cortical amyloid deposition using PET imaging
por: Collij, Lyduine E., et al.
Publicado: (2020)

An exploratory clinical study of p38α kinase inhibition in Alzheimer's disease
por: Scheltens, Philip, et al.
Publicado: (2018)

Spatial-Temporal Patterns of β-Amyloid Accumulation: A Subtype and Stage Inference Model Analysis
por: Collij, Lyduine E., et al.
Publicado: (2022)

Retinal layer thickness in preclinical Alzheimer's disease
por: van de Kreeke, Jacoba A., et al.
Publicado: (2019)

Amyloid-β and APOE genotype predict memory decline in cognitively unimpaired older individuals independently of Alzheimer’s disease polygenic risk score
por: Tomassen, Jori, et al.
Publicado: (2022)

Clinical outcomes up to 9 years after [(18)F]flutemetamol amyloid-PET in a symptomatic memory clinic population
por: Collij, Lyduine E., et al.
Publicado: (2023)

Simulating the effect of cerebral blood flow changes on regional quantification of [(18)F]flutemetamol and [(18)F]florbetaben studies
por: Heeman, Fiona, et al.
Publicado: (2020)

Optimized dual-time-window protocols for quantitative [(18)F]flutemetamol and [(18)F]florbetaben PET studies
por: Heeman, Fiona, et al.
Publicado: (2019)

Associations of Brain Pathology Cognitive and Physical Markers With Age in Cognitively Normal Individuals Aged 60–102 Years
por: Legdeur, Nienke, et al.
Publicado: (2019)

Onset of Preclinical Alzheimer Disease in Monozygotic Twins
por: Konijnenberg, Elles, et al.
Publicado: (2021)

Amyloid‐β PET and CSF in an autopsy‐confirmed cohort
por: Reimand, Juhan, et al.
Publicado: (2020)

Optical coherence tomography angiography in preclinical Alzheimer’s disease
por: van de Kreeke, Jacoba Alida, et al.
Publicado: (2020)

Longitudinal retinal layer changes in preclinical Alzheimer’s disease
por: van de Kreeke, Jacoba A., et al.
Publicado: (2020)

Regional associations of white matter hyperintensities and early cortical amyloid pathology
por: Lorenzini, Luigi, et al.
Publicado: (2022)

Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging
por: Lopes Alves, Isadora, et al.
Publicado: (2021)

Impact of cerebral blood flow and amyloid load on SUVR bias
por: Heeman, Fiona, et al.
Publicado: (2022)

Quantitative amyloid PET in Alzheimer's disease: the AMYPAD prognostic and natural history study
por: Lopes Alves, Isadora, et al.
Publicado: (2020)

Cerebral rituximab uptake in multiple sclerosis: A (89)Zr-immunoPET pilot study
por: Hagens, Marloes HJ, et al.
Publicado: (2017)

Retinal thickness as a potential biomarker in patients with amyloid-proven early- and late-onset Alzheimer's disease
por: den Haan, Jurre, et al.
Publicado: (2019)

Plasma biomarkers predict amyloid pathology in cognitively normal monozygotic twins after 10 years
por: den Braber, Anouk, et al.
Publicado: (2023)

Genetically identical twin-pair difference models support the amyloid cascade hypothesis
por: Coomans, Emma M, et al.
Publicado: (2023)

Eigenvector Centrality Dynamics From Resting-State fMRI: Gender and Age Differences in Healthy Subjects
por: Wink, Alle Meije
Publicado: (2019)

Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer's disease
por: Scheltens, Nienke M.E., et al.
Publicado: (2018)

Genetically identical twins show comparable tau PET load and spatial distribution
por: Coomans, Emma M, et al.
Publicado: (2022)

PET and CSF amyloid-β status are differently predicted by patient features: information from discordant cases
por: Reimand, Juhan, et al.
Publicado: (2019)

Reproducibility of quantitative (R)-[(11)C]verapamil studies
por: van Assema, Daniëlle ME, et al.
Publicado: (2012)

Cognitive reserve and clinical progression in Alzheimer disease: A paradoxical relationship
por: van Loenhoud, Anna Catharina, et al.
Publicado: (2019)

Eigenvector centrality dynamics are related to Alzheimer’s disease pathological changes in non-demented individuals
por: Lorenzini, Luigi, et al.
Publicado: (2023)

Widespread Disruption of Functional Brain Organization in Early-Onset Alzheimer’s Disease
por: Adriaanse, Sofie M., et al.
Publicado: (2014)

Performance of a [(18)F]Flortaucipir PET Visual Read Method Across the Alzheimer Disease Continuum and in Dementia With Lewy Bodies
por: Coomans, Emma M., et al.
Publicado: (2023)

Why Is Amyloid-β PET Requested After Performing CSF Biomarkers?
por: Reimand, Juhan, et al.
Publicado: (2020)

Test-Retest Variability of Relative Tracer Delivery Rate as Measured by [(11)C]PiB
por: Heeman, Fiona, et al.
Publicado: (2021)

Semi-quantitative cerebral blood flow parameters derived from non-invasive [(15)O]H(2)O PET studies
por: Koopman, Thomas, et al.
Publicado: (2017)

Test-retest variability of quantitative [(11)C]PIB studies in Alzheimer’s disease
por: Tolboom, Nelleke, et al.
Publicado: (2009)

Optimization of supervised cluster analysis for extracting reference tissue input curves in (R)-[(11)C]PK11195 brain PET studies
por: Yaqub, Maqsood, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6j75673chgd4qukff17tfemhnd