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Basilar invagination associated with chiari malformation type I: A literature review
Basilar invagination (BI) and Chiari malformation type I (CM-I) are very important anomalies that introduce instability and compression in the occipitocervical transition region and have complex clinical characteristics. These anomalies vary according to the affected structures. The present study re...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculdade de Medicina / USP
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448527/ https://www.ncbi.nlm.nih.gov/pubmed/30970117 http://dx.doi.org/10.6061/clinics/2019/e653 |
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author | Brito, José Nazareno Pearce de Oliveira dos Santos, Bruna Afonso Nascimento, Isys Fialho Martins, Leonardo Augusto Tavares, Cléciton Braga |
author_facet | Brito, José Nazareno Pearce de Oliveira dos Santos, Bruna Afonso Nascimento, Isys Fialho Martins, Leonardo Augusto Tavares, Cléciton Braga |
author_sort | Brito, José Nazareno Pearce de Oliveira |
collection | PubMed |
description | Basilar invagination (BI) and Chiari malformation type I (CM-I) are very important anomalies that introduce instability and compression in the occipitocervical transition region and have complex clinical characteristics. These anomalies vary according to the affected structures. The present study revises current knowledge regarding the anatomy, anatomo-physiology, clinical manifestations, and radiological findings of these entities and the associated surgical treatment approaches. A bibliographic survey was performed through a search in the Medline, PubMed, SciELO, Science and LILACS databases. When associated, these craniovertebral malformations result in neurological deficits due to neural parenchyma compression; however, the presence of microtraumas due to repetitive lesions caused by the bulb and cervical marrow instability has been highlighted as a determinant dysfunction. Surgical treatment is controversial and has many technical variations. Surgery is also challenging due to the complex anatomical characteristics and biomechanics of this region. Nevertheless, advances have been achieved in our understanding of related mechanisms, and compression and atlantoaxial instability are considered key elements when selecting the surgical approach. |
format | Online Article Text |
id | pubmed-6448527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Faculdade de Medicina / USP |
record_format | MEDLINE/PubMed |
spelling | pubmed-64485272019-04-09 Basilar invagination associated with chiari malformation type I: A literature review Brito, José Nazareno Pearce de Oliveira dos Santos, Bruna Afonso Nascimento, Isys Fialho Martins, Leonardo Augusto Tavares, Cléciton Braga Clinics (Sao Paulo) Review Article Basilar invagination (BI) and Chiari malformation type I (CM-I) are very important anomalies that introduce instability and compression in the occipitocervical transition region and have complex clinical characteristics. These anomalies vary according to the affected structures. The present study revises current knowledge regarding the anatomy, anatomo-physiology, clinical manifestations, and radiological findings of these entities and the associated surgical treatment approaches. A bibliographic survey was performed through a search in the Medline, PubMed, SciELO, Science and LILACS databases. When associated, these craniovertebral malformations result in neurological deficits due to neural parenchyma compression; however, the presence of microtraumas due to repetitive lesions caused by the bulb and cervical marrow instability has been highlighted as a determinant dysfunction. Surgical treatment is controversial and has many technical variations. Surgery is also challenging due to the complex anatomical characteristics and biomechanics of this region. Nevertheless, advances have been achieved in our understanding of related mechanisms, and compression and atlantoaxial instability are considered key elements when selecting the surgical approach. Faculdade de Medicina / USP 2019-04-04 2019 /pmc/articles/PMC6448527/ /pubmed/30970117 http://dx.doi.org/10.6061/clinics/2019/e653 Text en Copyright © 2019 CLINICS https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Brito, José Nazareno Pearce de Oliveira dos Santos, Bruna Afonso Nascimento, Isys Fialho Martins, Leonardo Augusto Tavares, Cléciton Braga Basilar invagination associated with chiari malformation type I: A literature review |
title | Basilar invagination associated with chiari malformation type I: A literature review |
title_full | Basilar invagination associated with chiari malformation type I: A literature review |
title_fullStr | Basilar invagination associated with chiari malformation type I: A literature review |
title_full_unstemmed | Basilar invagination associated with chiari malformation type I: A literature review |
title_short | Basilar invagination associated with chiari malformation type I: A literature review |
title_sort | basilar invagination associated with chiari malformation type i: a literature review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448527/ https://www.ncbi.nlm.nih.gov/pubmed/30970117 http://dx.doi.org/10.6061/clinics/2019/e653 |
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