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ROS amplification drives mouse spermatogonial stem cell self-renewal
Reactive oxygen species (ROS) play critical roles in self-renewal division for various stem cell types. However, it remains unclear how ROS signals are integrated with self-renewal machinery. Here, we report that the MAPK14/MAPK7/BCL6B pathway creates a positive feedback loop to drive spermatogonial...
Autores principales: | Morimoto, Hiroko, Kanastu-Shinohara, Mito, Ogonuki, Narumi, Kamimura, Satoshi, Ogura, Atsuo, Yabe-Nishimura, Chihiro, Mori, Yoshifumi, Morimoto, Takeshi, Watanabe, Satoshi, Otsu, Kinya, Yamamoto, Takuya, Shinohara, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448598/ https://www.ncbi.nlm.nih.gov/pubmed/30940732 http://dx.doi.org/10.26508/lsa.201900374 |
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