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Model of influenza virus acidification

Internal acidification of the influenza virus, mediated by the M2 proton channel, is a key step in its life cycle. The interior M1 protein shell dissolves at pH~5.5 to 6.0, allowing the release of vRNA to the cytoplasm upon fusion of the viral envelope with the endosomal membrane. Previous models ha...

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Detalles Bibliográficos
Autores principales: Akole, Ajit, Warner, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448856/
https://www.ncbi.nlm.nih.gov/pubmed/30946753
http://dx.doi.org/10.1371/journal.pone.0214448

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