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Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells

Due to their ability to preferentially induce cell death in tumor cells, while sparing healthy cells, TNF-related apoptosis-inducing ligand (TRAIL) and agonistic anti-TRAIL-R1 or anti-TRAIL-R2-specific antibodies are under clinical investigations for cancer-treatment. However, TRAIL-Rs may also indu...

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Detalles Bibliográficos
Autores principales:	Willms, Anna, Schittek, Hella, Rahn, Sascha, Sosna, Justyna, Mert, Ufuk, Adam, Dieter, Trauzold, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448923/ https://www.ncbi.nlm.nih.gov/pubmed/30947287 http://dx.doi.org/10.1371/journal.pone.0214847

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