Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity

AIMS/HYPOTHESIS: Subcutaneous adipocyte hypertrophy is associated with insulin resistance and increased risk of type 2 diabetes, and predicts its future development independent of obesity. In humans, subcutaneous adipose tissue hypertrophy is a consequence of impaired adipocyte precursor cell recrui...

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Detalles Bibliográficos
Autores principales: Longo, Michele, Raciti, Gregory A., Zatterale, Federica, Parrillo, Luca, Desiderio, Antonella, Spinelli, Rosa, Hammarstedt, Ann, Hedjazifar, Shahram, Hoffmann, Jenny M., Nigro, Cecilia, Mirra, Paola, Fiory, Francesca, Formisano, Pietro, Miele, Claudia, Smith, Ulf, Beguinot, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448963/
https://www.ncbi.nlm.nih.gov/pubmed/29067487
http://dx.doi.org/10.1007/s00125-017-4471-4

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