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Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP

ATP synthase produces the majority of cellular energy in most cells. We have previously reported cryo-EM maps of autoinhibited E. coli ATP synthase imaged without addition of nucleotide (Sobti et al. 2016), indicating that the subunit ε engages the α, β and γ subunits to lock the enzyme and prevent...

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Detalles Bibliográficos
Autores principales: Sobti, Meghna, Ishmukhametov, Robert, Bouwer, James C, Ayer, Anita, Suarna, Cacang, Smith, Nicola J, Christie, Mary, Stocker, Roland, Duncan, Thomas M, Stewart, Alastair G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449082/
https://www.ncbi.nlm.nih.gov/pubmed/30912741
http://dx.doi.org/10.7554/eLife.43864