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Epilepsy-Induced Reduction in HCN Channel Expression Contributes to an Increased Excitability in Dorsal, But Not Ventral, Hippocampal CA1 Neurons
CA1 neurons in epileptic animals are vulnerable to selective changes in ion channel expression, called acquired channelopathies, which can increase the excitability of a neuron. Under normal conditions there is a gradient of ion channel expression and intrinsic excitability along the longitudinal, d...
Autores principales: | Arnold, Elizabeth C., McMurray, Calli, Gray, Richard, Johnston, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449163/ https://www.ncbi.nlm.nih.gov/pubmed/30957013 http://dx.doi.org/10.1523/ENEURO.0036-19.2019 |
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