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Epilepsy-Induced Reduction in HCN Channel Expression Contributes to an Increased Excitability in Dorsal, But Not Ventral, Hippocampal CA1 Neurons

CA1 neurons in epileptic animals are vulnerable to selective changes in ion channel expression, called acquired channelopathies, which can increase the excitability of a neuron. Under normal conditions there is a gradient of ion channel expression and intrinsic excitability along the longitudinal, d...

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Detalles Bibliográficos
Autores principales: Arnold, Elizabeth C., McMurray, Calli, Gray, Richard, Johnston, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449163/
https://www.ncbi.nlm.nih.gov/pubmed/30957013
http://dx.doi.org/10.1523/ENEURO.0036-19.2019

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