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FLOT1 promotes tumor development, induces epithelial–mesenchymal transition, and modulates the cell cycle by regulating the Erk/Akt signaling pathway in lung adenocarcinoma

BACKGROUND: FLOT1 is a scaffolding protein of lipid rafts that is believed to be involved in numerous cellular processes. However, few studies have explored the function of FLOT1 in the development of lung adenocarcinoma (LUAD) and the underlying mechanisms of FLOT1 activity. METHODS: FLOT1 knockdow...

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Detalles Bibliográficos
Autores principales:	Zhang, Louqian, Mao, Yuan, Mao, Qixing, Fan, Weifei, Xu, Li, Chen, Yan, Xu, Lin, Wang, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449277/ https://www.ncbi.nlm.nih.gov/pubmed/30838797 http://dx.doi.org/10.1111/1759-7714.13027

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