Cargando…
A novel 3D in vitro model of glioblastoma reveals resistance to temozolomide which was potentiated by hypoxia
PURPOSE: Glioblastoma (GBM) is the most common invasive malignant brain tumour in adults. It is traditionally investigated in vitro by culturing cells as a monolayer (2D culture) or as neurospheres (clusters enriched in cancer stem cells) but neither system accurately reflects the complexity of the...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449313/ https://www.ncbi.nlm.nih.gov/pubmed/30694423 http://dx.doi.org/10.1007/s11060-019-03107-0 |