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Natural quorum sensing inhibitors effectively downregulate gene expression of Pseudomonas aeruginosa virulence factors
At present, anti-virulence drugs are being considered as potential therapeutic alternatives and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit virulence factors essential for establishing infection and pathogenesis through targeting non-essential metaboli...
Autores principales: | Ahmed, Syed A. K. S., Rudden, Michelle, Smyth, Thomas J., Dooley, James S. G., Marchant, Roger, Banat, Ibrahim M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449319/ https://www.ncbi.nlm.nih.gov/pubmed/30852658 http://dx.doi.org/10.1007/s00253-019-09618-0 |
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