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The asymmetry of plasma membranes and their cholesterol content influence the uptake of cisplatin
The composition of the plasma membrane of malignant cells is thought to influence the cellular uptake of cisplatin and to take part in developing resistance to this widespread anti-cancer drug. In this work we study the permeation of cisplatin through the model membranes of normal and cancer cells u...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449338/ https://www.ncbi.nlm.nih.gov/pubmed/30948733 http://dx.doi.org/10.1038/s41598-019-41903-w |