Cargando…
Vinculin Force Sensor Detects Tumor-Osteocyte Interactions
This study utilized a Förster resonance energy transfer (FRET)-based molecular tension sensor and live cell imaging to evaluate the effect of osteocytes, a mechanosensitive bone cell, on the migratory behavior of tumor cells. Two cell lines derived from MDA-MB-231 breast cancer cells were transfecte...
Autores principales: | Li, Fangjia, Chen, Andy, Reeser, Andrew, Wang, Yue, Fan, Yao, Liu, Shengzhi, Zhao, Xinyu, Prakash, Rahul, Kota, Divya, Li, Bai-Yan, Yokota, Hiroki, Liu, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449341/ https://www.ncbi.nlm.nih.gov/pubmed/30948840 http://dx.doi.org/10.1038/s41598-019-42132-x |
Ejemplares similares
-
Overexpression of Lrp5 enhanced the anti-breast cancer effects of osteocytes in bone
por: Liu, Shengzhi, et al.
Publicado: (2021) -
Attraction and Compaction of Migratory Breast Cancer Cells by Bone Matrix Proteins through Tumor-Osteocyte Interactions
por: Chen, Andy, et al.
Publicado: (2018) -
Inhibition of the Growth of Breast Cancer-Associated Brain Tumors by the Osteocyte-Derived Conditioned Medium
por: Sano, Tomohiko, et al.
Publicado: (2021) -
Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion
por: Fan, Yao, et al.
Publicado: (2020) -
Mechanical stability of αT-catenin and its activation by force for vinculin binding
por: Pang, Si Ming, et al.
Publicado: (2019)