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Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

Protein aggregation is a complex process resulting in the formation of heterogeneous mixtures of aggregate populations that are closely linked to neurodegenerative conditions, such as Alzheimer’s disease. Here, we find that soluble aggregates formed at different stages of the aggregation process of...

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Detalles Bibliográficos
Autores principales:	De, Suman, Wirthensohn, David C., Flagmeier, Patrick, Hughes, Craig, Aprile, Francesco A., Ruggeri, Francesco S., Whiten, Daniel R., Emin, Derya, Xia, Zengjie, Varela, Juan A., Sormanni, Pietro, Kundel, Franziska, Knowles, Tuomas P. J., Dobson, Christopher M., Bryant, Clare, Vendruscolo, Michele, Klenerman, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449370/ https://www.ncbi.nlm.nih.gov/pubmed/30948723 http://dx.doi.org/10.1038/s41467-019-09477-3

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