Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements

Essentially all cellular processes are orchestrated by protein-protein interactions (PPIs). In recent years, affinity purification coupled to mass spectrometry (AP-MS) has been the preferred method to identify cellular PPIs. Here we present a microfluidic-based AP-MS workflow, called on-chip AP-MS,...

Descripción completa

Detalles Bibliográficos
Autores principales: Furlan, Cristina, Dirks, René A. M., Thomas, Peter C., Jones, Robert C., Wang, Jing, Lynch, Mark, Marks, Hendrik, Vermeulen, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449397/
https://www.ncbi.nlm.nih.gov/pubmed/30948724
http://dx.doi.org/10.1038/s41467-019-09533-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449397/
https://www.ncbi.nlm.nih.gov/pubmed/30948724
http://dx.doi.org/10.1038/s41467-019-09533-y

Ejemplares similares