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Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements
Essentially all cellular processes are orchestrated by protein-protein interactions (PPIs). In recent years, affinity purification coupled to mass spectrometry (AP-MS) has been the preferred method to identify cellular PPIs. Here we present a microfluidic-based AP-MS workflow, called on-chip AP-MS,...
Autores principales: | Furlan, Cristina, Dirks, René A. M., Thomas, Peter C., Jones, Robert C., Wang, Jing, Lynch, Mark, Marks, Hendrik, Vermeulen, Michiel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449397/ https://www.ncbi.nlm.nih.gov/pubmed/30948724 http://dx.doi.org/10.1038/s41467-019-09533-y |
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