Silencing an insulin-induced lncRNA, LncASIR, impairs the transcriptional response to insulin signalling in adipocytes

Long noncoding RNA(lncRNA)s are new regulators governing the metabolism in adipose tissue. In this study, we aimed to understand how lncRNAs respond to insulin signalling and explore whether lncRNAs have a functional role in insulin signalling pathway. We treated primary adipocyte cultures with insu...

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Detalles Bibliográficos
Autores principales: Degirmenci, Ufuk, Li, Jia, Lim, Yen Ching, Siang, Diana Teh Chee, Lin, Shibo, Liang, Hui, Sun, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449399/
https://www.ncbi.nlm.nih.gov/pubmed/30948776
http://dx.doi.org/10.1038/s41598-019-42162-5

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