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NKG2D/NKG2-Ligand Pathway Offers New Opportunities in Cancer Treatment
The antitumor functions of NK cells are regulated by the integration of positive and negative signals triggered by numerous membrane receptors present on the NK cells themselves. Among the main activating receptors, NKG2D binds several stress-induced molecules on tumor targets. Engagement of NKG2D b...
Autores principales: | Frazao, Alexandra, Rethacker, Louise, Messaoudene, Meriem, Avril, Marie-Françoise, Toubert, Antoine, Dulphy, Nicolas, Caignard, Anne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449444/ https://www.ncbi.nlm.nih.gov/pubmed/30984204 http://dx.doi.org/10.3389/fimmu.2019.00661 |
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