Distinct metabolic patterns during microglial remodeling by oleate and palmitate

Microglial activation by oleate and palmitate differentially modulates brain inflammatory status. However, the metabolic reprogramming supporting these reactive phenotypes remains unknown. Employing real-time metabolic measurements and lipidomic analysis, we show that both fatty acids promote microg...

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Detalles Bibliográficos
Autores principales: Chausse, Bruno, Kakimoto, Pamela A., Caldeira-da-Silva, Camille C., Chaves-Filho, Adriano B., Yoshinaga, Marcos Y., da Silva, Railmara Pereira, Miyamoto, Sayuri, Kowaltowski, Alicia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449521/
https://www.ncbi.nlm.nih.gov/pubmed/30867255
http://dx.doi.org/10.1042/BSR20190072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449521/
https://www.ncbi.nlm.nih.gov/pubmed/30867255
http://dx.doi.org/10.1042/BSR20190072

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