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Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study

INTRODUCTION: Sarcomas are rare malignancies with aggressive biological behavior. They are categorized into soft and hard tissue types. The main objective of this study was to analyze the prevalence of head and neck sarcomas (HNS) among the Iranian population. MATERIALS AND METHODS: The pathology fi...

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Autores principales: Atarbashi-Moghadam, Saede, Emami Razavi, Amir Nader, Salehi Zalani, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449527/
https://www.ncbi.nlm.nih.gov/pubmed/30989075
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author Atarbashi-Moghadam, Saede
Emami Razavi, Amir Nader
Salehi Zalani, Saman
author_facet Atarbashi-Moghadam, Saede
Emami Razavi, Amir Nader
Salehi Zalani, Saman
author_sort Atarbashi-Moghadam, Saede
collection PubMed
description INTRODUCTION: Sarcomas are rare malignancies with aggressive biological behavior. They are categorized into soft and hard tissue types. The main objective of this study was to analyze the prevalence of head and neck sarcomas (HNS) among the Iranian population. MATERIALS AND METHODS: The pathology files derived from Iran National Tumor Bank of Cancer Institute in Imam Khomeini Hospital, affiliated to Tehran University of Medical Sciences, Tehran, Iran, served as the source of the materials for this study. All cases diagnosed with head and neck sarcoma were included in the study. The recorded data included the patient’s age, gender, tumor location, and rates of recurrence and metastasis. RESULTS: Investigation of the pathology files of the patients referring to the center under study during a 10-year period resulted in the identification of 183 HNS cases, 96.17% of which were primary. Generally, the prevalence of this disease was at its highest level in patients within the age range of 30-60 years with a male to female ratio of 1.4. The recurrence and metastasis rates of HNS were 32.38% and 5%, respectively. Osteosarcoma was detected as the most common type of sarcoma. Soft tissue sarcomas constituted 69.3% of the lesions with a male predilection. The patients afflicted with this type of sarcoma had a mean age of 45.88 years. Furthermore, hard tissue sarcomas comprised 30.68% of the sarcoma cases with a mean age of 36.22 years and a female predilection. The commonest lesion was osteosarcoma, and the most typical location was the mandible. CONCLUSION: In the current study, head and neck sarcomas were most often observed in patients within the age range of 30-60 years with a male predilection. Osteosarcoma was identified as the most common type of sarcoma. Studies addressing rare lesions with a large sample size facilitate the recognition of the demographic data and histopathologic variation which may contribute to a correct diagnosis.
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spelling pubmed-64495272019-04-15 Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study Atarbashi-Moghadam, Saede Emami Razavi, Amir Nader Salehi Zalani, Saman Iran J Otorhinolaryngol Original Article INTRODUCTION: Sarcomas are rare malignancies with aggressive biological behavior. They are categorized into soft and hard tissue types. The main objective of this study was to analyze the prevalence of head and neck sarcomas (HNS) among the Iranian population. MATERIALS AND METHODS: The pathology files derived from Iran National Tumor Bank of Cancer Institute in Imam Khomeini Hospital, affiliated to Tehran University of Medical Sciences, Tehran, Iran, served as the source of the materials for this study. All cases diagnosed with head and neck sarcoma were included in the study. The recorded data included the patient’s age, gender, tumor location, and rates of recurrence and metastasis. RESULTS: Investigation of the pathology files of the patients referring to the center under study during a 10-year period resulted in the identification of 183 HNS cases, 96.17% of which were primary. Generally, the prevalence of this disease was at its highest level in patients within the age range of 30-60 years with a male to female ratio of 1.4. The recurrence and metastasis rates of HNS were 32.38% and 5%, respectively. Osteosarcoma was detected as the most common type of sarcoma. Soft tissue sarcomas constituted 69.3% of the lesions with a male predilection. The patients afflicted with this type of sarcoma had a mean age of 45.88 years. Furthermore, hard tissue sarcomas comprised 30.68% of the sarcoma cases with a mean age of 36.22 years and a female predilection. The commonest lesion was osteosarcoma, and the most typical location was the mandible. CONCLUSION: In the current study, head and neck sarcomas were most often observed in patients within the age range of 30-60 years with a male predilection. Osteosarcoma was identified as the most common type of sarcoma. Studies addressing rare lesions with a large sample size facilitate the recognition of the demographic data and histopathologic variation which may contribute to a correct diagnosis. Mashhad University of Medical Sciences 2019-03 /pmc/articles/PMC6449527/ /pubmed/30989075 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Atarbashi-Moghadam, Saede
Emami Razavi, Amir Nader
Salehi Zalani, Saman
Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study
title Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study
title_full Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study
title_fullStr Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study
title_full_unstemmed Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study
title_short Prevalence of Head and Neck Sarcoma in a Major Cancer Center in Iran- A 10-Year Study
title_sort prevalence of head and neck sarcoma in a major cancer center in iran- a 10-year study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449527/
https://www.ncbi.nlm.nih.gov/pubmed/30989075
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