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Pyrophosphate Stimulates the Phosphate-Sodium Symporter of Trypanosoma brucei Acidocalcisomes and Saccharomyces cerevisiae Vacuoles

Inorganic pyrophosphate (PP(i)) is a by-product of biosynthetic reactions and has bioenergetic and regulatory roles in a variety of cells. Here we show that PP(i) and other pyrophosphate-containing compounds, including polyphosphate (polyP), can stimulate sodium-dependent depolarization of the membr...

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Detalles Bibliográficos
Autores principales: Potapenko, Evgeniy, Cordeiro, Ciro D., Huang, Guozhong, Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449605/
https://www.ncbi.nlm.nih.gov/pubmed/30944211
http://dx.doi.org/10.1128/mSphere.00045-19