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Eternal sunshine of the spotless cycle

Understanding the quantitative principles underlying the durations of each of the four cell cycle phases has remained a challenge, despite the extensive knowledge on the molecular components and mechanisms related to cell cycle control. In their recent study, Purvis and colleagues (Chao et al, 2019)...

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Detalles Bibliográficos
Autores principales: Gelens, Lendert, Santos, Silvia DM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449696/
https://www.ncbi.nlm.nih.gov/pubmed/30952682
http://dx.doi.org/10.15252/msb.20198864
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author Gelens, Lendert
Santos, Silvia DM
author_facet Gelens, Lendert
Santos, Silvia DM
author_sort Gelens, Lendert
collection PubMed
description Understanding the quantitative principles underlying the durations of each of the four cell cycle phases has remained a challenge, despite the extensive knowledge on the molecular components and mechanisms related to cell cycle control. In their recent study, Purvis and colleagues (Chao et al, 2019) quantify cell cycle phase durations in human cells and propose a model whereby cell cycle progression in single cells is a succession of uncoupled, memoryless phases, each composed of a characteristic rate and number of steps.
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spelling pubmed-64496962019-04-15 Eternal sunshine of the spotless cycle Gelens, Lendert Santos, Silvia DM Mol Syst Biol News & Views Understanding the quantitative principles underlying the durations of each of the four cell cycle phases has remained a challenge, despite the extensive knowledge on the molecular components and mechanisms related to cell cycle control. In their recent study, Purvis and colleagues (Chao et al, 2019) quantify cell cycle phase durations in human cells and propose a model whereby cell cycle progression in single cells is a succession of uncoupled, memoryless phases, each composed of a characteristic rate and number of steps. John Wiley and Sons Inc. 2019-04-05 /pmc/articles/PMC6449696/ /pubmed/30952682 http://dx.doi.org/10.15252/msb.20198864 Text en © 2019 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle News & Views
Gelens, Lendert
Santos, Silvia DM
Eternal sunshine of the spotless cycle
title Eternal sunshine of the spotless cycle
title_full Eternal sunshine of the spotless cycle
title_fullStr Eternal sunshine of the spotless cycle
title_full_unstemmed Eternal sunshine of the spotless cycle
title_short Eternal sunshine of the spotless cycle
title_sort eternal sunshine of the spotless cycle
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449696/
https://www.ncbi.nlm.nih.gov/pubmed/30952682
http://dx.doi.org/10.15252/msb.20198864
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