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Manipulation of gene expression by an ecdysone-inducible gene switch in tumor xenografts

BACKGROUND: Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional study of newly discovered genes in tumor formation and progression. The popularity of the ecdysone inducible gene switch system has le...

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Detalles Bibliográficos
Autores principales: Karns, Larry R, Kisielewski, Anne, Gulding, Kathryn M, Theodorescu, Dan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64497/
https://www.ncbi.nlm.nih.gov/pubmed/11782290
http://dx.doi.org/10.1186/1472-6750-1-11