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Type II Restriction of Bacteriophage DNA With 5hmdU-Derived Base Modifications

To counteract bacterial defense systems, bacteriophages (phages) make extensive base modifications (substitutions) to block endonuclease restriction. Here we evaluated Type II restriction of three thymidine (T or 5-methyldeoxyuridine, 5mdU) modified phage genomes: Pseudomonas phage M6 with 5-(2-amin...

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Detalles Bibliográficos
Autores principales:	Flodman, Kiersten, Tsai, Rebecca, Xu, Michael Y., Corrêa, Ivan R., Copelas, Alyssa, Lee, Yan-Jiun, Xu, Ming-Qun, Weigele, Peter, Xu, Shuang-yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449724/ https://www.ncbi.nlm.nih.gov/pubmed/30984133 http://dx.doi.org/10.3389/fmicb.2019.00584

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