Homoharringtonine Combined with the Heat Shock Protein 90 Inhibitor IPI504 in the Treatment of FLT3-ITD Acute Myeloid Leukemia

As a heterogeneous group of clonal disorders, acute myeloid leukemia with internal tandem duplication of fms-like tyrosine kinase 3 (FLT3-ITD) mutation usually shows an inferior prognosis. In the present study, we found that homoharringtonine (HHT), a protein translation inhibitor of plant alkaloid...

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Detalles Bibliográficos
Autores principales: Wu, Zhaoxing, Zhuang, Haifeng, Yu, Qingfeng, Zhang, Xuzhao, Jiang, Xudong, Lu, Xiaoya, Xu, Ying, Yang, Linlin, Wu, Bowen, Ma, An, Zhang, Lei, Xiao, Xibin, Liang, Yun, Gao, Ruilan, Shen, Jianping, Xu, Rongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449739/
https://www.ncbi.nlm.nih.gov/pubmed/30953928
http://dx.doi.org/10.1016/j.tranon.2019.02.016

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