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The central role of nucleic acids in the pathogenesis of systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease whose pathogenesis can be conceptualized by a model based on a central role for immune complexes (ICs) between antinuclear antibodies and nucleic acids. According to this model, ICs can promote pathogenesis by two main mechanisms:...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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F1000 Research Limited
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449788/ https://www.ncbi.nlm.nih.gov/pubmed/31001416 http://dx.doi.org/10.12688/f1000research.17959.1 |