WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming

Differentiated cells are epigenetically stable, but can be reprogrammed to pluripotency by expression of the OSKM transcription factors. Despite significant effort, relatively little is known about the cellular requirements for reprogramming and how they affect the properties of induced pluripotent...

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Detalles Bibliográficos
Autores principales: Peñalosa-Ruiz, Georgina, Bousgouni, Vicky, Gerlach, Jan P., Waarlo, Susan, van de Ven, Joris V., Veenstra, Tim E., Silva, José C.R., van Heeringen, Simon J., Bakal, Chris, Mulder, Klaas W., Veenstra, Gert Jan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449870/
https://www.ncbi.nlm.nih.gov/pubmed/30880078
http://dx.doi.org/10.1016/j.stemcr.2019.02.006

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