Cargando…
Network-based characterization of drug-protein interaction signatures with a space-efficient approach
BACKGROUND: Characterization of drug-protein interaction networks with biological features has recently become challenging in recent pharmaceutical science toward a better understanding of polypharmacology. RESULTS: We present a novel method for systematic analyses of the underlying features charact...
Autores principales: | Tabei, Yasuo, Kotera, Masaaki, Sawada, Ryusuke, Yamanishi, Yoshihiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449886/ https://www.ncbi.nlm.nih.gov/pubmed/30953486 http://dx.doi.org/10.1186/s12918-019-0691-1 |
Ejemplares similares
-
Inferring protein domains associated with drug side effects based on drug-target interaction network
por: Iwata, Hiroaki, et al.
Publicado: (2013) -
Predicting inhibitory and activatory drug targets by chemically and genetically perturbed transcriptome signatures
por: Sawada, Ryusuke, et al.
Publicado: (2018) -
DINIES: drug–target interaction network inference engine based on supervised analysis
por: Yamanishi, Yoshihiro, et al.
Publicado: (2014) -
Metabolome-scale de novo pathway reconstruction using regioisomer-sensitive graph alignments
por: Yamanishi, Yoshihiro, et al.
Publicado: (2015) -
Simultaneous prediction of enzyme orthologs from chemical transformation patterns for de novo metabolic pathway reconstruction
por: Tabei, Yasuo, et al.
Publicado: (2016)