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Highly glycosylated CD147 promotes hemorrhagic transformation after rt-PA treatment in diabetes: a novel therapeutic target?

BACKGROUND: Diabetes is known to be a main risk factor of post-stroke hemorrhagic transformation following recombinant tissue plasminogen activator (rt-PA) therapy. However, the mechanism through which diabetes exacerbates hemorrhagic transformation is insufficiently understood. We aimed to verify t...

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Detalles Bibliográficos
Autores principales:	Xie, Yanan, Wang, Yingzhe, Ding, Hongyan, Guo, Min, Wang, Xun, Dong, Qiang, Cui, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449915/ https://www.ncbi.nlm.nih.gov/pubmed/30953513 http://dx.doi.org/10.1186/s12974-019-1460-1

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