Integrative analysis of DNA methylation in discordant twins unveils distinct architectures of systemic sclerosis subsets

BACKGROUND: Systemic sclerosis (SSc) is a rare autoimmune fibrosing disease with an incompletely understood genetic and non-genetic etiology. Defining its etiology is important to allow the development of effective predictive, preventative, and therapeutic strategies. We conducted this epigenomic st...

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Detalles Bibliográficos
Autores principales: Ramos, Paula S., Zimmerman, Kip D., Haddad, Sandra, Langefeld, Carl D., Medsger, Thomas A., Feghali-Bostwick, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449959/
https://www.ncbi.nlm.nih.gov/pubmed/30947741
http://dx.doi.org/10.1186/s13148-019-0652-y

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